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Placental and fetal involvement by maternal malignancy: A report of rectal carcinoma and review of the literature

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Abstract

A case of maternal adenocarcinoma of the rectum with extensive intervillous involvement is presented and the western world's literature is reviewed. Detectable fetal involvement by maternal malignancy is rare, although maternofetal transmission of malignant cells is probably more frequent than realized. The factors affecting transmission of tumor to the fetus are: tumor cell type, maternal arterial dissemination, intervillous sequestration, transvillous passage, fetal dissemination, and fetal response.

Original languageEnglish
Pages (from-to)1023-1034
Number of pages12
JournalAmerican Journal of Obstetrics and Gynecology
Volume116
Issue number7
DOIs
StatePublished - 1973
Externally publishedYes

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