12 Scopus citations


Pituitary hormones have traditionally been thought to exert specific, but limited function on target tissues. More recently, the discovery of these hormones and their receptors in organs such as the skeleton suggests that pituitary hormones have more ubiquitous functions. Here, we discuss the interaction of growth hormone (GH), follicle stimulating hormone (FSH), thyroid stimulating hormone (TSH), adrenocorticotrophic hormone (ACTH), prolactin, oxytocin and arginine vasopressin (AVP) with bone. The direct skeletal action of pituitary hormones therefore provides new insights and therapeutic opportunities for metabolic bone diseases, prominently osteoporosis.

Original languageEnglish
Pages (from-to)85-94
Number of pages10
JournalHormone Molecular Biology and Clinical Investigation
Issue number2
StatePublished - 1 Nov 2016


  • glycoprotein hormone coupled receptor (GPCR)
  • osteoblast
  • osteoclast
  • pituitary-bone axis


Dive into the research topics of 'Pituitary-bone connection in skeletal regulation'. Together they form a unique fingerprint.

Cite this