Pitfalls in Morphologic Diagnosis of Pathogens: Lessons Learned From the Pseudo-Cystoisospora Epidemic

Arun Gopinath, Ahmad Alkhasawneh, Aysha Mubeen, Raafat Makary, Ibraheem Mohammed, Brett Baskovich

Research output: Contribution to journalReview articlepeer-review

Abstract

Multiple groups have recently reported involvement of the gallbladder mucosa of immunocompetent patients by cystoisospora organisms. However, this has recently been disproved with the support of molecular and ultrastructural studies. Here we present a summary of these events, recounting how this pseudo-Cystoisospora epidemic began and ended. This review also highlights the important role played by ancillary techniques in supplementing the morphologic diagnosis of pathogens.

Original languageEnglish
Pages (from-to)169-173
Number of pages5
JournalInternational Journal of Surgical Pathology
Volume29
Issue number2
DOIs
StatePublished - Apr 2021
Externally publishedYes

Keywords

  • Cystoisospora
  • epithelial
  • gallbladder
  • gastric
  • inclusion
  • molecular
  • ultrastructural

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