Piracetam Reduces Alcohol Withdrawal in Mice without Potentiating Alcohol Sedative Effects

Michael Serby; David J. Segamick; Donna Mandio Cordasco; John Rotrosen

doi:10.1111/j.1530-0277.1982.tb05016.x

Piracetam Reduces Alcohol Withdrawal in Mice without Potentiating Alcohol Sedative Effects

Michael Serby
, David J. Segamick
, Donna Mandio Cordasco
, John Rotrosen

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

Piracetam reduced the intensity of withdrawal behavior in mice that had been exposed to ethanol for 4 days. However, in contrast to other antiwithdrawal agents, piracetam did not potentiate the sedative effects of acute ethanol administration. While the mechanism of action of piracetam is unknown, these findings suggest that piracetam elicits its antiwithdrawal effects by a mechanism differing from that of other agents.

Original language	English
Pages (from-to)	520-522
Number of pages	3
Journal	Alcoholism: Clinical and Experimental Research
Volume	6
Issue number	4
DOIs	https://doi.org/10.1111/j.1530-0277.1982.tb05016.x
State	Published - Sep 1982
Externally published	Yes

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title = "Piracetam Reduces Alcohol Withdrawal in Mice without Potentiating Alcohol Sedative Effects",

abstract = "Piracetam reduced the intensity of withdrawal behavior in mice that had been exposed to ethanol for 4 days. However, in contrast to other antiwithdrawal agents, piracetam did not potentiate the sedative effects of acute ethanol administration. While the mechanism of action of piracetam is unknown, these findings suggest that piracetam elicits its antiwithdrawal effects by a mechanism differing from that of other agents.",

author = "Michael Serby and Segamick, \{David J.\} and Cordasco, \{Donna Mandio\} and John Rotrosen",

year = "1982",

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T1 - Piracetam Reduces Alcohol Withdrawal in Mice without Potentiating Alcohol Sedative Effects

AU - Serby, Michael

AU - Segamick, David J.

AU - Cordasco, Donna Mandio

AU - Rotrosen, John

PY - 1982/9

Y1 - 1982/9

N2 - Piracetam reduced the intensity of withdrawal behavior in mice that had been exposed to ethanol for 4 days. However, in contrast to other antiwithdrawal agents, piracetam did not potentiate the sedative effects of acute ethanol administration. While the mechanism of action of piracetam is unknown, these findings suggest that piracetam elicits its antiwithdrawal effects by a mechanism differing from that of other agents.

AB - Piracetam reduced the intensity of withdrawal behavior in mice that had been exposed to ethanol for 4 days. However, in contrast to other antiwithdrawal agents, piracetam did not potentiate the sedative effects of acute ethanol administration. While the mechanism of action of piracetam is unknown, these findings suggest that piracetam elicits its antiwithdrawal effects by a mechanism differing from that of other agents.

UR - https://www.scopus.com/pages/publications/0020448364

U2 - 10.1111/j.1530-0277.1982.tb05016.x

DO - 10.1111/j.1530-0277.1982.tb05016.x

M3 - Article

C2 - 6758623

AN - SCOPUS:0020448364

SN - 0145-6008

VL - 6

SP - 520

EP - 522

JO - Alcoholism: Clinical and Experimental Research

JF - Alcoholism: Clinical and Experimental Research

IS - 4

ER -

Piracetam Reduces Alcohol Withdrawal in Mice without Potentiating Alcohol Sedative Effects

Abstract

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