TY - JOUR
T1 - Piracetam Reduces Alcohol Withdrawal in Mice without Potentiating Alcohol Sedative Effects
AU - Serby, Michael
AU - Segamick, David J.
AU - Cordasco, Donna Mandio
AU - Rotrosen, John
PY - 1982/9
Y1 - 1982/9
N2 - Piracetam reduced the intensity of withdrawal behavior in mice that had been exposed to ethanol for 4 days. However, in contrast to other antiwithdrawal agents, piracetam did not potentiate the sedative effects of acute ethanol administration. While the mechanism of action of piracetam is unknown, these findings suggest that piracetam elicits its antiwithdrawal effects by a mechanism differing from that of other agents.
AB - Piracetam reduced the intensity of withdrawal behavior in mice that had been exposed to ethanol for 4 days. However, in contrast to other antiwithdrawal agents, piracetam did not potentiate the sedative effects of acute ethanol administration. While the mechanism of action of piracetam is unknown, these findings suggest that piracetam elicits its antiwithdrawal effects by a mechanism differing from that of other agents.
UR - http://www.scopus.com/inward/record.url?scp=0020448364&partnerID=8YFLogxK
U2 - 10.1111/j.1530-0277.1982.tb05016.x
DO - 10.1111/j.1530-0277.1982.tb05016.x
M3 - Article
C2 - 6758623
AN - SCOPUS:0020448364
SN - 0145-6008
VL - 6
SP - 520
EP - 522
JO - Alcoholism: Clinical and Experimental Research
JF - Alcoholism: Clinical and Experimental Research
IS - 4
ER -