Physiologic changes in regional cerebral blood flow defined by xenon-enhanced CT scanning

B. P. Drayer, S. K. Wolfson, M. Boehnke, M. Dujovny, A. E. Rosenbaum, E. E. Cook

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

With adequate concentrations of commercially available nonradioactive xenon an enhancement of brain substance was readily demonstrated by computed tomography (CT). By performing successive CT scans at a fixed brain level following xenon inhalation, the partition coefficient and clearance of xenon as well as the regional cerebral blood flow (rCBF) could be calculated. The expected physiologic alterations in rCBF with acute cerebral infarction and changes in arterial CO2 were accurately defined by xenon-enhanced CT scanning affirming the potential future applications of this technique.

Original languageEnglish
Pages (from-to)220-223
Number of pages4
JournalNeuroradiology
Volume16
Issue number1
DOIs
StatePublished - Dec 1978
Externally publishedYes

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