TY - JOUR
T1 - Physicians' Health Study
T2 - Aspirin and Primary Prevention of Coronary Heart Disease
AU - The Steering Committee of the Physicians' Health Study Research Group
AU - Khaw, Kay Tee
AU - Patrono, Carlo
AU - Fitzgerald, Garret A.
AU - Kaplan, Robert M.
AU - Bader, Max
AU - Taylor, D. W.
AU - Barnett, H. J.M.
AU - Baudoin, Claude
AU - Balkau, Beverley
AU - Eschwege, Eveline
AU - Fuster, Valentin
AU - Cohen, Marc
AU - Halperin, Jonathan
PY - 1989/12/28
Y1 - 1989/12/28
N2 - To the Editor: Both the U.S. Physicians' Health Study (July 20 issue)1 and the British Doctors' Study2 found no significant differences in mortality from all causes or from cardiovascular disease between aspirin-treated and placebo or untreated groups. The British study also found no differences in event rates for nonfatal or fatal myocardial infarction. In contrast, the U.S. study reported a significant reduction in rates of nonfatal and fatal myocardial infarction in the aspirin-treated group, leading to the authors' conclusion that aspirin treatment is protective overall against coronary heart disease. In the U.S. study, although the death rates for acute myocardial….
AB - To the Editor: Both the U.S. Physicians' Health Study (July 20 issue)1 and the British Doctors' Study2 found no significant differences in mortality from all causes or from cardiovascular disease between aspirin-treated and placebo or untreated groups. The British study also found no differences in event rates for nonfatal or fatal myocardial infarction. In contrast, the U.S. study reported a significant reduction in rates of nonfatal and fatal myocardial infarction in the aspirin-treated group, leading to the authors' conclusion that aspirin treatment is protective overall against coronary heart disease. In the U.S. study, although the death rates for acute myocardial….
UR - http://www.scopus.com/inward/record.url?scp=0024980429&partnerID=8YFLogxK
U2 - 10.1056/NEJM198912283212610
DO - 10.1056/NEJM198912283212610
M3 - Letter
C2 - 2594041
AN - SCOPUS:0024980429
SN - 0028-4793
VL - 321
SP - 1825
EP - 1828
JO - New England Journal of Medicine
JF - New England Journal of Medicine
IS - 26
ER -