@article{ad17f275364749c9bbda0aea0d5a205c,
title = "Physical mapping and cloning of RAD56",
abstract = "Here we report the physical mapping of the rad56-1 mutation to the NAT3 gene, which encodes the catalytic subunit of the NatB N-terminal acetyltransferase in Saccharomyces cerevisiae. Mutation of RAD56 causes sensitivity to X-rays, methyl methanesulfonate, zeocin, camptothecin and hydroxyurea, but not to UV light, suggesting that N-terminal acetylation of specific DNA repair proteins is important for efficient DNA repair.",
keywords = "Acetylation, DNA repair, Saccharomyces cerevisiae",
author = "Mathiasen, {David P.} and Irene Gallina and Germann, {Susanne M.} and Wissam Hamou and Morgane El{\'e}ou{\"e}t and Sara Thodberg and Nadine Eckert-Boulet and John Game and Michael Lisby",
note = "Funding Information: We thank members of the Lisby and Holmberg laboratories for helpful discussions on this work, and Rodney Rothstein, Hannah Klein and Ian Hickson for sharing reagents. This work was supported by The Danish Agency for Science, Technology and Innovation , the Villum Kann Rasmussen Foundation , the Lundbeck Foundation , the European Research Council (ERC) to M.L., I.G. and D.P.M., and the Deutscher Akademischer Auslandsdienst (DAAD) scholarship to S.M.G. We are grateful to the NBRP for providing the rad56-1 strain.",
year = "2013",
month = apr,
day = "25",
doi = "10.1016/j.gene.2013.01.044",
language = "English",
volume = "519",
pages = "182--186",
journal = "Gene",
issn = "0378-1119",
publisher = "Elsevier B.V.",
number = "1",
}