Physical location of tumor suppressor gene bcl-2 in maize chromosomes by FISH

Zheng Yang, Chen Leng Cai, Yi Qing Guo, Yun Chun Song, Li Hua Liu, Hou Jin Zhang

Research output: Contribution to journalArticlepeer-review


To analyze the presence of homologous sequences of human tumor supprossor gene bcl-2 in maize and rice, Southern hybridization was performed and positive signals were detected in these two species' genomes. FISH also was carried out for physical location of the bcl-2 homologous sequences in maize chromosomes. bcl-2 was hybridized onto the long arm of the fourth and the seventh chromosomes. The detection rates of FISH were 8. 10% and 6. 63%. The percentage distances from centromere to detection sites were 58. 07±4. 90 and 80. 34±3. 12 respectively. These results may provide important clues of the further research of the molecular mechanisms regulating the plant programmed cell death, and it may also benefit to further research on the relationship of programmed cell death between plants and animals.

Original languageEnglish
Pages (from-to)192-194
Number of pages3
JournalWuhan Daxue Xuebao/Journal of Wuhan University
Issue number2
StatePublished - 1999
Externally publishedYes


  • FISH
  • Homologous sequences
  • Maize
  • Programmed cell death
  • bcl-2


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