Photodynamic therapy for nonmelanoma skin cancers: Current review and update

Nathalie C. Zeitouni, Allan R. Oseroff, Sherry Shieh

Research output: Contribution to journalArticlepeer-review

145 Scopus citations

Abstract

Photodynamic therapy (PDT) is a therapeutic modality involving the use of a photosensitizing agent activated by light to destroy tumor cells. Over the past 25 years, PDT has been shown useful in the treatment of actinic keratoses and certain nonmelanoma skin cancers, such as Bowen's disease and basal cell carcinoma. We review the current data available for PDT with systemic photofrin and topical 5-aminolevulinic acid (ALA). PDT offers many advantages including its non-invasiveness and its ability to treat multiple lesions simultaneously and is, therefore, an interesting alternative for treating certain skin malignancies.

Original languageEnglish
Pages (from-to)1133-1136
Number of pages4
JournalMolecular Immunology
Volume39
Issue number17-18
DOIs
StatePublished - Jul 2003
Externally publishedYes

Keywords

  • ALA
  • Nonmelanoma skin cancer
  • Photodynamic therapy
  • Photofrin

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