TY - JOUR
T1 - Photodynamic therapy for nonmelanoma skin cancers
T2 - Current review and update
AU - Zeitouni, Nathalie C.
AU - Oseroff, Allan R.
AU - Shieh, Sherry
PY - 2003/7
Y1 - 2003/7
N2 - Photodynamic therapy (PDT) is a therapeutic modality involving the use of a photosensitizing agent activated by light to destroy tumor cells. Over the past 25 years, PDT has been shown useful in the treatment of actinic keratoses and certain nonmelanoma skin cancers, such as Bowen's disease and basal cell carcinoma. We review the current data available for PDT with systemic photofrin and topical 5-aminolevulinic acid (ALA). PDT offers many advantages including its non-invasiveness and its ability to treat multiple lesions simultaneously and is, therefore, an interesting alternative for treating certain skin malignancies.
AB - Photodynamic therapy (PDT) is a therapeutic modality involving the use of a photosensitizing agent activated by light to destroy tumor cells. Over the past 25 years, PDT has been shown useful in the treatment of actinic keratoses and certain nonmelanoma skin cancers, such as Bowen's disease and basal cell carcinoma. We review the current data available for PDT with systemic photofrin and topical 5-aminolevulinic acid (ALA). PDT offers many advantages including its non-invasiveness and its ability to treat multiple lesions simultaneously and is, therefore, an interesting alternative for treating certain skin malignancies.
KW - ALA
KW - Nonmelanoma skin cancer
KW - Photodynamic therapy
KW - Photofrin
UR - http://www.scopus.com/inward/record.url?scp=0038771211&partnerID=8YFLogxK
U2 - 10.1016/S0161-5890(03)00083-X
DO - 10.1016/S0161-5890(03)00083-X
M3 - Article
C2 - 12835091
AN - SCOPUS:0038771211
SN - 0161-5890
VL - 39
SP - 1133
EP - 1136
JO - Molecular Immunology
JF - Molecular Immunology
IS - 17-18
ER -