Perspectives on protein crystallisation

Takashi Ochi, Victor M. Bolanos-Garcia, Vivian Stojanoff, Abel Moreno

Research output: Contribution to journalArticlepeer-review

12 Scopus citations

Abstract

This final part on 'perspectives' is focused on new strategies that can be used to crystallise proteins and improve the crystal quality of macromolecular complexes using any of the methods reviewed in this focused issue. Some advantages and disadvantages, limitations, and plausible applications to high-resolution X-ray crystallography are discussed.

Original languageEnglish
Pages (from-to)56-63
Number of pages8
JournalProgress in Biophysics and Molecular Biology
Volume101
Issue number1-3
DOIs
StatePublished - Nov 2009
Externally publishedYes

Keywords

  • Counter-diffusion
  • Crystallisation
  • DNA-repair proteins
  • Drug discovery
  • Gel
  • Lif1p-Lig4p
  • Protein crystal growth

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