TY - JOUR
T1 - Perspectives From Patients and Gastroenterologists on De-escalating Therapy for Crohn's Disease
AU - BIOCYCLE group
AU - Siegel, Corey A.
AU - Thompson, Kimberly D.
AU - Walls, Danielle
AU - Gollins, Jan
AU - Buisson, Anne
AU - Olympie, Alain
AU - Beaugerie, Laurent
AU - Colombel, Jean Frederic
AU - Louis, Edouard
N1 - Funding Information:
Funding This project receives funding from the European Union's Horizon 2020 research and innovation program under grant agreement No 633168 -BIOCYCLE (PHC-13-2014).
Funding Information:
The authors thank the Crohn's and Colitis Foundation for their support and their assistance with grant management.
Funding Information:
Funding This project receives funding from the European Union’s Horizon 2020 research and innovation program under grant agreement No 633168 -BIOCYCLE (PHC-13-2014).
Publisher Copyright:
© 2021 AGA Institute
PY - 2021/2
Y1 - 2021/2
N2 - In Crohn's disease, combination therapy with anti–tumor necrosis factor (anti-TNF) agents and azathioprine/mercaptopurine has been shown to be superior to monotherapy with one of these treatments alone.1 This combination has its best success rate when used early in the course of treatment.2 However, because of the significant cost of these drugs and concerns over long-term side effects,3,4 many patients and providers often ask about stopping one or both of these medications.
AB - In Crohn's disease, combination therapy with anti–tumor necrosis factor (anti-TNF) agents and azathioprine/mercaptopurine has been shown to be superior to monotherapy with one of these treatments alone.1 This combination has its best success rate when used early in the course of treatment.2 However, because of the significant cost of these drugs and concerns over long-term side effects,3,4 many patients and providers often ask about stopping one or both of these medications.
UR - http://www.scopus.com/inward/record.url?scp=85099183508&partnerID=8YFLogxK
U2 - 10.1016/j.cgh.2019.11.062
DO - 10.1016/j.cgh.2019.11.062
M3 - Short survey
C2 - 31887442
AN - SCOPUS:85099183508
SN - 1542-3565
VL - 19
SP - 403
EP - 405
JO - Clinical Gastroenterology and Hepatology
JF - Clinical Gastroenterology and Hepatology
IS - 2
ER -