Perioperative risks associated with cervical spondylotic myelopathy based on surgical treatment strategies

Angel Macagno, Shian Liu, Bryan J. Marascalchi, Sun Yang, Anthony J. Boniello, John A. Bendo, Virginie C. Lafage, Peter G. Passias

Research output: Contribution to journalArticlepeer-review

15 Scopus citations


Background Few studies have provided nationwide estimates of patient characteristics and procedure-related complications, or examined postsurgical outcomes for patients with cervical spondylotic myelopathy (CSM) comparatively with respect to surgical approach. The objective of this study is to identify patients at risk for morbidity and mortality directly related with the selected approach, report an overall nation-wide complication rate for each approach against which surgeons can compare themselves, and direct future research to improve patient outcomes. Methods Patients surgically treated for CSM were retrospectively identified using ICD-9-CM codes from the Nationwide Inpatient Sample (NIS) database. Four cohorts were compared for demographics and hospital system-related data: anterior (ACDF, ACCF), posterior decompression without fusion, decompression with posterior fusion, and combined anterior-posterior. Multivariate analysis was also used to determine the odds ratio of morbidity and mortality among the cohorts. Results 54,416 discharges were identified between 2001 and 2010: 34,400 anterior, 9,014 decompression procedures without fusion, 8,741 decompression procedures with posterior fusion, and 2,261 combined anterior-posterior. Groups were statistically different with respect to age, length of hospital stay, mortality, and complications. Groups were statistically different for Deyo score except between posterior decompression only and combined approaches. Using multivariate analysis and adjusting for covariates, the combined (2.74[2.18-3.44]) and laminectomy (1.22[1.04-1.44]) cohorts had an increased risk of mortality when compared to anterior alone. Conclusion These findings are the first to determine the rates and odds of perioperative risks directly related to combined anterior-posterior procedures. This study provides clinically useful data for surgeons to educate patients and direct future research to improve patient outcomes.

Original languageEnglish
Article number24
JournalInternational Journal of Spine Surgery
StatePublished - 1 Jan 2015
Externally publishedYes


  • Anterior
  • Cervical spondylotic myelopathy
  • Combined
  • Laminectomy
  • Laminoplasty
  • Nation-wide trends
  • Procedure-related complications


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