Perianal Goblet Cell Carcinoid With Pagetoid Spread

Dianne Grunes, Michelle Kang Kim, David B. Chessin, Rona D. Yaeger, Stephen C. Ward

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

We present a case of perianal goblet cell carcinoid with pagetoid spread. Goblet cell carcinoid, also known as adenocarcinoid tumor, predominantly arises as a primary appendiceal tumor and contains nests of neuroendocrine and mucin-containing cells. When this tumor type is seen in other sites it usually represents a metastasis. We present the case of an 81-year-old woman with a perianal mass. Histologic and immunohistochemical examination following surgical excision showed a goblet cell carcinoid demonstrating pagetoid spread along the perianal squamous mucosa. There was no evidence of a primary appendiceal tumor by history or imaging studies. To our knowledge, this is the first report of a goblet cell carcinoid presenting in this manner. The patient died due to complications of metastatic disease 26 months after initial diagnosis.

Original languageEnglish
Pages (from-to)788-791
Number of pages4
JournalInternational Journal of Surgical Pathology
Volume27
Issue number7
DOIs
StatePublished - 1 Oct 2019

Keywords

  • goblet cell carcinoid
  • pagetoid spread
  • perianal

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