Percutaneous device closure for secundum-type atrial septal defect: Short and intermediate-term results

Seifollah Abdi, Reza Kiani, Mahmood Momtahen, Hossein Ali Basiri, Mohssen Maadani, Safar Ali Abdolrahimi, Iraj Firozi, Hamid Reza Sanati, Farshad Shakerian, Ata Firoozi, Negar Salehi, Ali Zahedmehr

Research output: Contribution to journalArticlepeer-review

9 Scopus citations


BACKGROUND: Device closure of an isolated secundum type atrial septal defect (ASD) has been used as an alternative method for open surgical closure with comparable success and lower morbidity. In this study we evaluated the procedural success and mid-term follow-up results of percutaneous closure of secundum ASD with an Amplatzer™Septal Occluder(ASO) device or a Figula ASD occluder device. METHODS: From June 2001 to January 2009, 74 consecutive patients were scheduled for percutaneous device closure in two centers in Tehran, Iran. All patients had a stretched defect diameter of 30mm or less. After using a sizing balloon to measure the stop-flow diameter, device implantation was performed under the guidance of a trans-esophageal echocardiography (TEE).The size was generally 1 - 2 mm larger than the stretched diameter. Patients were followed for an average of 11 ±4 months. RESULTS: The median stretched diameter of the defect was 20.7±4.8 mm (range: 8 - 30 mm).A total of 73 devices were used in this study. Device closure was successful in 72 (97.2%) out of 74 patients. Repositioning of the device was required in one patient. Major complications(including significant residual shunt and device embolization) occurred in 3 (4%) patients.There was no procedure-related mortality in our patients. Mild-to-moderate residual shunt was detectable in 10 (13.7%) patients immediately following the procedure and in 5 (6.7%) patients 24 hours after the procedure. None had residual flow across the device at the end of the follow-up period. CONCLUSION: Device closure of ASD has a safety profile comparable to open surgical repair and can effectively close the defect with excellent procedural and mid-term results.

Original languageEnglish
Pages (from-to)693-695
Number of pages3
JournalArchives of Iranian Medicine
Issue number11
StatePublished - Nov 2012
Externally publishedYes


  • Amplatzer™ ASD closure device
  • Figula ASD closure device
  • Percutaneous ASD closure
  • Secundum atrial septal defect


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