Peptic ulcer disease

Neville D. Bamji, Ariel A. Benson

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

1 Scopus citations


Gastroduodenal ulcers form as the result of the breakdown of mucosal defense mechanisms against acid and enzymes that are present in the gastrointestinal tract. The principal risk factors for the development of peptic ulcer disease include Helicobacter pylori and non-steroidal anti-inflammatory drug (NSAID) use. Definitive diagnosis of peptic ulcer disease is accomplished with endoscopy. Management of peptic ulcer disease includes endoscopic procedures for bleeding ulcers, antisecretory therapy to reduce gastroduodenal acid, treatment of H. pylori, and avoidance of gastroduodenal irritants (such as NSAIDs).

Original languageEnglish
Title of host publicationGastroenterology
Number of pages10
ISBN (Electronic)9781118932759
ISBN (Print)9781118519967
StatePublished - 1 Jan 2014


  • Endoscopy
  • Gastritis
  • Gastropathy
  • Helicobacter pylori
  • Peptic ulcer disease


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