Abstract
Pentamidine isethionate inhibits growth of Saccharomyces cerevisiae. Inhibition requires lower drug concentrations under respiratory than fermentative growth conditions. Pentamidine-resistant strains bear heritable resistance mutations. Tested mutations are dominant to wild type sensitivity. These mutations may identify cellular targets of pentamidine and potential mechanisms of fungal pentamidine resistance.
| Original language | English |
|---|---|
| Pages (from-to) | 70S-71S |
| Journal | Journal of Eukaryotic Microbiology |
| Volume | 38 |
| Issue number | 6 |
| State | Published - 1991 |
| Externally published | Yes |