Pentafecta outcomes of 230 cases of robotic-assisted radical prostatectomy with bilateral neurovascular bundle preservation

Yen Chuan Ou, Chun Kuang Yang, Hsun Ming Kang, Kuangh Si Chang, John Wang, Siu Wan Hung, Min Che Tung, Ashutosh K. Tewari, Vipul R. Patel

Research output: Contribution to journalArticlepeer-review

25 Scopus citations

Abstract

Aim: We analyzed pentafecta outcomes [complication-free, continence, potency, negative surgical margins (NSM)], biochemical recurrence (BCR)-free] of 230 patients undergoing robotic-assisted radical prostatectomy (RARP) with bilateral neurovascular (NVB) preservation. Patients and Methods: Patient outcomes (group I, cases 1- 115; group II, cases 116-230) were assessed prospectively. Definitions were: continence, using no pads; potency, ability to achieve/maintain erections firm enough for sexual intercourse; positive surgical margin, presence of tumor tissue on inked specimen surface; and BCR, two consecutive PSA levels >0.2 ng/ml after RALP. Results: The mean patient age was 62.5 years, mean PSA=8.62 ng/ml. The complication-free rate was 93.9% (216/230), continence rate 98.3% (226/230), potency 86.1% (198/230), NSM 77.0% (177/230) and BCR-free 92.6% (213/230 ). The trifecta rate (continence, potency, BCR-free) was 81.7% (188/230). The pentafecta rate was 60.4% (139/230). Conclusion: Pentafecta is the new standard of outcomes for RARP with bilateral NVB, with patient selection and reduced positive surgical margins attaining best outcomes.

Original languageEnglish
Pages (from-to)5007-5014
Number of pages8
JournalAnticancer Research
Volume35
Issue number9
StatePublished - 1 Sep 2015
Externally publishedYes

Keywords

  • Biochemical recurrence
  • Laparoscopy
  • Pentafecta
  • Prostate cancer
  • Radical prostatectomy
  • Robotics

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