Pediatric Low Vitamin D Treatment Guideline Recommendations: An Integrative Review

This integrative review found 7 professional clinical practice guidelines or recommendations for treating low vitamin D (LVD) or vitamin D deficiency (VDD) in infants, children, and adolescents. Treatment recommendation considerations varied by age group, severity, daily versus weekly dosing, treatment length, need for follow-up testing and maintenance therapy after treatment completion. These inconsistencies make treatment recommendations for health care providers difficult to navigate. Terminology variations for LVD or VDD are discussed. Results reviewed with the Appraisal of Guidelines, Research and Evaluation II process showed mixed results with the lowest scores in Rigor of Development and Applicability domains.