Acute iron poisoning may lead to life-threatening hepatotoxicity. We present the cases of two pediatric patients with hepatotoxicity following intentional iron ingestion that progressed rapidly to fulminant hepatic failure despite treatment with deferoxamine. Liver transplantation was lifesaving in both patients. These cases emphasize the need for a high index of suspicion for iron ingestion, close monitoring for liver toxicity, and timely consideration for liver transplantation.

Original languageEnglish
Article numbere12994
JournalPediatric Transplantation
Issue number6
StatePublished - Sep 2017


  • hepatotoxicity
  • ingestion
  • iron
  • liver
  • pediatric
  • transplant


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