Pediatric herpes simplex virus infections: an evidence-based approach to treatment.

Jennifer E. Sanders, Sylvia E. Garcia

Research output: Contribution to journalReview articlepeer-review

16 Scopus citations


Herpes simplex virus is a common virus that causes a variety of clinical presentations ranging from mild to life-threatening. Orolabial and genital herpes are common disorders that can often be managed in an outpatient setting; however, some patients do present to the emergency department with those conditions, and emergency clinicians should be aware of possible complications in the pediatric population. Neonatal herpes is a rare disorder, but prompt recognition and initiation of antiviral therapy is imperative, as the morbidity and mortality of the disease is high. Herpes encephalitis is an emergency that also requires a high index of suspicion to diagnose. Herpes simplex virus is also responsible for a variety of other clinical presentations, including herpes gladiatorum, herpetic whitlow, eczema herpeticum, and ocular herpes. This issue reviews the common clinical presentations of the herpes simplex virus, the life-threatening infections that require expedient identification and management, and recommended treatment regimens.

Original languageEnglish
Pages (from-to)1-19; quiz 19
JournalPediatric emergency medicine practice
Issue number1
StatePublished - Jan 2014


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