Pediatric cancer: Brain tumors

Surabhi Batra, Birte Wistinghausen

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

Pediatric brain tumors account for 20% of childhood malignancies, making them the second largest group of childhood cancers. The presentation varies depending location. In the preschool age child, infratentorial tumors are more common and patients present with signs of increased intracranial pressure, ataxia, and cranial nerve deficits. In school age children and adolescents, supratentorial tumors become more prevalent with focal deficits and/or seizures depending on location. Signs of increased intracranial pressure can be subtle in preschool children and include developmental delay, macrocephaly, and unexplained vomiting. The largest group of tumors are gliomas, most commonly low grade pylocytic astrocytomas. Medulloblastomas and ependymomas are more common in young children and can disseminate along the neuroaxis. Germ cell tumors, supratentorial primitive neuroectodermal tumors, are rare but can also disseminate.

Original languageEnglish
Title of host publicationOncology
Publisherwiley
Pages556-565
Number of pages10
ISBN (Electronic)9781119189596
ISBN (Print)9781119189558
DOIs
StatePublished - 30 Aug 2019
Externally publishedYes

Keywords

  • Diffuse intrinsic pontine glioma
  • Ependymoma
  • Germ cell tumor
  • Medulloblastoma
  • Pediatric brain tumor
  • Primitive neuroectodermal tumor
  • Pylocytic astrocytoma

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