TY - JOUR
T1 - Pattern electroretinograms and visual-evoked potentials in glaucoma and multiple sclerosis
AU - Bobak, P.
AU - Bodis-Wollner, I.
AU - Harnois, C.
AU - Maffei, L.
AU - Mylin, L.
AU - Podos, S.
AU - Thornton, J.
N1 - Funding Information:
Accepted for publication April 20, 1983. From the Departments of Ophthalmology (Drs. Bobak, Bodis-Wollner,, and Bodos), Neurology (Drs. Bodis-Wollner and Harnois, and L. Mylin), and Biostatistics (Dr. Thornton), Mount Sinai School of Medicine, New York, New York; and the Instituto di Neurofisiologia del C.N.R., Pisa, Italy (Dr. Maffei). This study was supported in part by grant EY01708 from the National Eye Institute; core center grant EY01867 and grants EY01701 and RR-00071 from the National Institutes of Health; grant NS 11631 from the Clinical Center for Research in Parkinson's and Allied Diseases; a research fellowship from the Fond de la Recherche en Sante du Quebec; and by an unrestricted grant from Research to Prevent Blindness, Inc., New York, New York. Reprint requests to I. Bodis-Wollner, M.D., 1200 Fifth Ave., New York, NY 10029.
PY - 1983/7
Y1 - 1983/7
N2 - Steady-state visual-evoked potentials and electroretinograms were simultaneously recorded in four patients with glaucoma and in five patients with multiple sclerosis. The stimuli included a homogenous field and a 2.3 cycles per degree sinusoidal grating that were counterphase modulated at the rate of 7.5 Hz. We used narrow bandwidth spectral analysis to measure the response amplitudes and signal-to-noise ratios. Transient pattern visual-evoked potentials (1 Hz) were also measured for latency in each eye. We found abnormal pattern electroretinograms, based on the absence of a significant second harmonic component, in three of the four glaucomatous eyes although the homogenous field electroretinograms were normal. In the patients with multiple sclerosis, the pattern electroretinograms were abnormal in two eyes, but the transient visual-evoked potential latency had the highest diagnostic yield (seven of ten eyes).
AB - Steady-state visual-evoked potentials and electroretinograms were simultaneously recorded in four patients with glaucoma and in five patients with multiple sclerosis. The stimuli included a homogenous field and a 2.3 cycles per degree sinusoidal grating that were counterphase modulated at the rate of 7.5 Hz. We used narrow bandwidth spectral analysis to measure the response amplitudes and signal-to-noise ratios. Transient pattern visual-evoked potentials (1 Hz) were also measured for latency in each eye. We found abnormal pattern electroretinograms, based on the absence of a significant second harmonic component, in three of the four glaucomatous eyes although the homogenous field electroretinograms were normal. In the patients with multiple sclerosis, the pattern electroretinograms were abnormal in two eyes, but the transient visual-evoked potential latency had the highest diagnostic yield (seven of ten eyes).
UR - http://www.scopus.com/inward/record.url?scp=0020596869&partnerID=8YFLogxK
U2 - 10.1016/0002-9394(83)90457-9
DO - 10.1016/0002-9394(83)90457-9
M3 - Article
C2 - 6869481
AN - SCOPUS:0020596869
SN - 0002-9394
VL - 96
SP - 72
EP - 83
JO - American Journal of Ophthalmology
JF - American Journal of Ophthalmology
IS - 1
ER -