Patient survival factors in paranasal sinus mucormycosis

Andrew Blitzer, William Lawson, Bert R. Meyers, Hugh F. Biller

Research output: Contribution to journalArticlepeer-review

241 Scopus citations


Analysis of 170 cases of paranasal sinus mucormycosis collected from the literature and 9 cases of our own revealed a 50% mortality for this disease. When analyzed according to decade, survival has increased to 70% in the cases reported from 1970-1979. There were no significant differences between the survivors and the fatalities when evaluated according to age, sex, laterality, or radiographic findings. There was a markedly poorer prognosis for those patients with hemiplegia, facial necrosis, and nasal deformity. The underlying disease was an important determinant of survival: 75% of patients with no systemic disease, 60% of diabetics, and 20% of patients with other disorders survived. Surgical debridement or radical resection and the use of amphotericin B significantly increased survival. Their combination further enhanced survival, especially in the diabetic.

Original languageEnglish
Pages (from-to)635-648
Number of pages14
Issue number4
StatePublished - Apr 1980


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