Patient partnership in cardiovascular clinical trials

Faiez Zannad, Cynthia Chauhan, Patrick O. Gee, Nick Hartshorne-Evans, Adrian F. Hernandez, Marilyn K. Mann, Robin Martinez, Roxana Mehran

Research output: Contribution to journalReview articlepeer-review

4 Scopus citations


Patients are ultimately the end-users of medical therapies and need to be actively integrated as contributors and decision-makers in the process of product development throughout product lifecycles. This is increasingly being recognized by patients, investigators, regulators, payers, sponsors, and medical journals. However, cardiovascular research remains behind other fields in terms of the extent of patient involvement and awareness of clinical trials in cardiovascular research. True patient partnerships in cardiovascular therapeutic development may permit more rapid recognition of unmet needs, ensure alignment of product development priorities with patient priorities, improve efficiency of trials (e.g. recruitment), and ensure outcomes of value to patients are being measured in trials (e.g. quality of life). This paper reviews ongoing initiatives and remaining opportunities to accomplish contributive patient involvement in cardiovascular clinical research.

Original languageEnglish
Pages (from-to)1432-1437
Number of pages6
JournalEuropean Heart Journal
Issue number14
StatePublished - 7 Apr 2022


  • Clinical trials
  • Drug development
  • Heart disease
  • Patient partner
  • Patient-centred care
  • Patient-oriented research
  • Patient-reported outcomes


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