Patient-Associated Predictors of 15- and 30-Day Readmission After Hospitalization for Acute Heart Failure

Juan F. Delgado, Andreu Ferrero Gregori, Laura Morán Fernández, Ramón Bascompte Claret, Andrés Grau Sepúlveda, Francisco Fernández-Avilés, José R. González-Juanatey, Rafael Vázquez García, Miguel Rivera Otero, Javier Segovia Cubero, Domingo Pascual Figal, Maria G. Crespo-Leiro, Jesús Alvarez-García, Juan Cinca, Fernando Arribas Ynsaurriaga

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


Background: Identifying readmission predictors in heart failure (HF) patients may help guide preventative efforts and save costs. We aimed to identify 15- and 30-day readmission predictors due to cardiovascular reasons. Methods and Results: A total of 1831 patients with acute HF admission were prospectively followed during a year. Patient-associated variables were gathered at admission/discharge and events during follow-up. A multivariate Fine and Gray competing risk regression model and a cumulative incidence function were used to identify predictors and build a risk score model for 15- and 30-day readmission. The 15- and 30-day readmission rates due to cardiovascular reasons were 7.1% and 13.9%. Previous acute myocardial infarction, congestive signs at discharge, and length of stay > 9 days were predictors of 15- and 30-day readmission, while much weight loss and large NT-ProBNP reduction were protective factors. The NT-ProBNP reduction was larger at 30 days (> 55%) vs 15 days (> 40%) to protect from readmission. Glomerular filtration rate at discharge < 60 mL/min/1.73m2 and > 1 previous admissions due to HF were predictors of 30-day readmission, while first post-discharge control at an HF unit was a protective factor. Conclusions: Previous identified factors for early readmission were confirmed. The NT-ProBNP reduction should be increased (> 55%) to protect from 30-day readmission.

Original languageEnglish
Pages (from-to)304-314
Number of pages11
JournalCurrent Heart Failure Reports
Issue number6
StatePublished - 1 Dec 2019
Externally publishedYes


  • Heart failure
  • NT-ProBNP
  • Predictive factors
  • Readmission


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