Pathophysiology of airway inflammation in asthma

Paula J. Busse, William W. Busse

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review


Asthma is a chronic disease of the airways that in most cases has its inception in early childhood with physiological hallmarks of increased airway inflammation, bronchial hyperresponsiveness, and airflow obstruction that is largely reversible. Clinically, asthmatic patients have symptoms of coughing (especially at night), shortness of breath, chest tightness, and wheezing. The diagnosis of asthma is made by these clinical symptoms and is confirmed by the demonstration of reversible airflow obstruction.

Original languageEnglish
Title of host publicationTherapeutic Targets in Airway Inflammation
PublisherCRC Press
Number of pages54
ISBN (Electronic)9780203911471
ISBN (Print)9780824709563
StatePublished - 1 Jan 2003


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