Patents and literature - Affinity-based separations and purifications

Jonathan S. Dordick

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

The separation and purification of biologically functional molecules (e.g., proteins, antibodies, peptides, hormones, low molecular weight biologicals) is of fundamental importance to biotechnology. Affinity separations have become a particularly attractive method for bioseparations due to their high degree of selectivity. Numerous affinity ligands have been prepared in recent years including lectins, nucleic acids, inhibitors, and immunoresponse agents. Furthermore, a variety of novel supports have been synthesized to aid in the development of commercially useful affinity separation systems. Recent US patents and scientific literature on affinity separations and purifications are surveyed. Patent abstracts are summarized individually and a list of literature references are given.

Original languageEnglish
Pages (from-to)93-109
Number of pages17
JournalApplied Biochemistry and Biotechnology
Volume27
Issue number1
DOIs
StatePublished - Jan 1991
Externally publishedYes

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