20 Scopus citations


Establishment of genomic imprints during early development involves concerted epigenetic mechanisms. Two recent studies by Terranova et al. (in this issue of Developmental Cell) and Pandey et al. (in a recent issue of Molecular Cell) have demonstrated that Polycomb group proteins (PcG) and the Kcnq1ot1 regulatory RNA, respectively, are indispensable for gene- and lineage-specific chromatin modification and compaction of the paternally imprinted Kcnq1 cluster.

Original languageEnglish
Pages (from-to)637-638
Number of pages2
JournalDevelopmental Cell
Issue number5
StatePublished - 11 Nov 2008


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