Paraneoplastic dermatoses associated with gynecologic and breast malignancies

Danielle Levine, Sheryl Miller, Najla Al-Dawsari, Orr Barak, Alice B. Gottlieb

Research output: Contribution to journalReview articlepeer-review

22 Scopus citations


Paraneoplastic dermatoses are a heterogeneous group of skin disorders that manifest an underlying internal malignancy. Early recognition of these cutaneous hallmarks offers an opportunity for early diagnosis, treatment of the internal malignancy and monitoring for tumor recurrence. The 9 most common paraneoplastic and metastatic cutaneous manifestations of malignancies found in women with gynecologic or breast disease are reviewed including a review of multicentric reticulohistiocytosis, dermatomyositis, malignant acanthosis nigricans, erythema gyratum repens, hypertrichosis lanuginosa acquisita, Sweet syndrome, Paget disease, extramammary Paget disease, and Sister Mary Joseph nodule. Target audience: General obstetricians & gynecologists, reproductive endocrinology & infertility specialists, radiologists. Learning objectives: After completion of this educational activity, the participant should be better able to identify cutaneous manifestations of gynecologic malignancies, evaluate patients with a thorough workup to screen those who have dermatoses suggestive of malignancy and assess patients with malignancy for the opportunity of early diagnosis and appropriate treatment.

Original languageEnglish
Pages (from-to)455-461
Number of pages7
JournalObstetrical and Gynecological Survey
Issue number7
StatePublished - Jul 2010
Externally publishedYes


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