Pancreatic mucinous cystic neoplasm in a transgender patient

Deshka Foster, Mohammad F. Shaikh, Elizabeth Gleeson, Blake D. Babcock, Jianping Lin, Robert T. Ownbey, Mark E. Hysell, Daniel Ringold, Wilbur B. Bowne

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


Background: Cystic pancreatic lesions are increasingly more frequent detected clinical entities. Mucinous cystic neoplasm (MCN) is a hormone-related pancreatic tumor (HRTP) with a strong predominance in young and middle-aged females. Case presentation: Here, we present the case of a 31-year-old surgically transgendered female-to-male patient with a history of alcoholic pancreatitis, on chronic testosterone therapy. He was found to have a pancreatic MCN and underwent distal pancreatectomy and splenectomy. Conclusion: To our knowledge, this is the first reported case of a transgender patient with a history of hormone replacement therapy (HRT) and pancreatic MCN. We consider possible mechanisms for the pathogenesis to explain this patient's neoplasm.

Original languageEnglish
Article number205
JournalWorld Journal of Surgical Oncology
Issue number1
StatePublished - 24 Jun 2015
Externally publishedYes


  • Hormone therapy
  • Pancreatic MCN
  • Transgender medicine


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