Pancreatic mucinous cystic neoplasm in a transgender patient

Deshka Foster; Mohammad F. Shaikh; Elizabeth Gleeson; Blake D. Babcock; Jianping Lin; Robert T. Ownbey; Mark E. Hysell; Daniel Ringold; Wilbur B. Bowne

doi:10.1186/s12957-015-0620-8

Pancreatic mucinous cystic neoplasm in a transgender patient

Deshka Foster, Mohammad F. Shaikh, Elizabeth Gleeson, Blake D. Babcock, Jianping Lin, Robert T. Ownbey, Mark E. Hysell, Daniel Ringold, Wilbur B. Bowne

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

Background: Cystic pancreatic lesions are increasingly more frequent detected clinical entities. Mucinous cystic neoplasm (MCN) is a hormone-related pancreatic tumor (HRTP) with a strong predominance in young and middle-aged females. Case presentation: Here, we present the case of a 31-year-old surgically transgendered female-to-male patient with a history of alcoholic pancreatitis, on chronic testosterone therapy. He was found to have a pancreatic MCN and underwent distal pancreatectomy and splenectomy. Conclusion: To our knowledge, this is the first reported case of a transgender patient with a history of hormone replacement therapy (HRT) and pancreatic MCN. We consider possible mechanisms for the pathogenesis to explain this patient's neoplasm.

Original language	English
Article number	205
Journal	World Journal of Surgical Oncology
Volume	13
Issue number	1
DOIs	https://doi.org/10.1186/s12957-015-0620-8
State	Published - 24 Jun 2015
Externally published	Yes

Keywords

Hormone therapy
Pancreatic MCN
Transgender medicine

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10.1186/s12957-015-0620-8

Cite this

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title = "Pancreatic mucinous cystic neoplasm in a transgender patient",

abstract = "Background: Cystic pancreatic lesions are increasingly more frequent detected clinical entities. Mucinous cystic neoplasm (MCN) is a hormone-related pancreatic tumor (HRTP) with a strong predominance in young and middle-aged females. Case presentation: Here, we present the case of a 31-year-old surgically transgendered female-to-male patient with a history of alcoholic pancreatitis, on chronic testosterone therapy. He was found to have a pancreatic MCN and underwent distal pancreatectomy and splenectomy. Conclusion: To our knowledge, this is the first reported case of a transgender patient with a history of hormone replacement therapy (HRT) and pancreatic MCN. We consider possible mechanisms for the pathogenesis to explain this patient's neoplasm.",

keywords = "Hormone therapy, Pancreatic MCN, Transgender medicine",

author = "Deshka Foster and Shaikh, {Mohammad F.} and Elizabeth Gleeson and Babcock, {Blake D.} and Jianping Lin and Ownbey, {Robert T.} and Hysell, {Mark E.} and Daniel Ringold and Bowne, {Wilbur B.}",

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doi = "10.1186/s12957-015-0620-8",

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T1 - Pancreatic mucinous cystic neoplasm in a transgender patient

AU - Foster, Deshka

AU - Shaikh, Mohammad F.

AU - Gleeson, Elizabeth

AU - Babcock, Blake D.

AU - Lin, Jianping

AU - Ownbey, Robert T.

AU - Hysell, Mark E.

AU - Ringold, Daniel

AU - Bowne, Wilbur B.

PY - 2015/6/24

Y1 - 2015/6/24

N2 - Background: Cystic pancreatic lesions are increasingly more frequent detected clinical entities. Mucinous cystic neoplasm (MCN) is a hormone-related pancreatic tumor (HRTP) with a strong predominance in young and middle-aged females. Case presentation: Here, we present the case of a 31-year-old surgically transgendered female-to-male patient with a history of alcoholic pancreatitis, on chronic testosterone therapy. He was found to have a pancreatic MCN and underwent distal pancreatectomy and splenectomy. Conclusion: To our knowledge, this is the first reported case of a transgender patient with a history of hormone replacement therapy (HRT) and pancreatic MCN. We consider possible mechanisms for the pathogenesis to explain this patient's neoplasm.

AB - Background: Cystic pancreatic lesions are increasingly more frequent detected clinical entities. Mucinous cystic neoplasm (MCN) is a hormone-related pancreatic tumor (HRTP) with a strong predominance in young and middle-aged females. Case presentation: Here, we present the case of a 31-year-old surgically transgendered female-to-male patient with a history of alcoholic pancreatitis, on chronic testosterone therapy. He was found to have a pancreatic MCN and underwent distal pancreatectomy and splenectomy. Conclusion: To our knowledge, this is the first reported case of a transgender patient with a history of hormone replacement therapy (HRT) and pancreatic MCN. We consider possible mechanisms for the pathogenesis to explain this patient's neoplasm.

KW - Hormone therapy

KW - Pancreatic MCN

KW - Transgender medicine

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Pancreatic mucinous cystic neoplasm in a transgender patient

Abstract

Keywords

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