This chapter presents the classification, incidence/prevalence, economic impact, etiology and risk factors, and pathology/pathogenesis of pancreas cancer. Pancreas cancer ranks as the fourth leading cause of cancer-related deaths in the USA and seventh in the world. The chapter also includes the potential pitfalls/common errors made regarding diagnosis of disease, diagnostic and treatment algorithms, prevention/management of complications, important scientific studies, evidence-based clinical data, and essential social guidelines for pancreas cancer. Combination chemotherapy as well as radiation therapy used in the neoadjuvant and adjuvant settings following curative resection has improved survival in patients with early stage pancreas cancer. Supportive care including interventions for obstructive jaundice has improved the quality of life for patients with pancreas cancer. Identification of environmental and genetic risk factors is paving the way towards earlier detection of pancreas cancer. Adenocarcinomas and neuroendocrine cancers of the pancreas have significant differences in prognosis. Response to intervention needs to be made through histologic and serologic evaluation.

Original languageEnglish
Title of host publicationOncology
Number of pages7
ISBN (Electronic)9781119189596
ISBN (Print)9781119189558
StatePublished - 30 Aug 2019


  • Combination chemotherapy
  • Curative resection
  • Diagnostic algorithms
  • Evidence-based clinical data
  • Neuroendocrine cancers
  • Pancreas cancer
  • Pancreatic adenocarcinomas
  • Radiation therapy
  • Treatment algorithms


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