Palladium-103 plaque brachytherapy for retinoblastoma: Long term follow up

Abhilasha Maheshwari, Paul T. Finger

Research output: Contribution to journalArticlepeer-review

Abstract

Purpose: Radiation has been used in the treatment of retinoblastoma. Herein, we present the novel use of palladium-103 plaque brachytherapy as primary treatment. Observation: An 8-year-old asymptomatic girl presented was found to have a solitary peripheral retinoblastoma in her right eye. She was treated with primary palladium-103 plaque brachytherapy (47.4 Gray over 5 consecutive days). A secondary, vitreous hemorrhage noted 46 months after irradiation was successfully controlled by laser tumor-demarcation. With 19-years follow up, there has been no clinical scleropathy, or local tumor recurrence. The eye yields 20/20 vision and there has been no systemic metastasis. Conclusion and importance: Palladium-103 plaque brachytherapy successfully controlled retinoblastoma, while preserving the globe, vision, and life.

Original languageEnglish
Article number101636
JournalAmerican Journal of Ophthalmology Case Reports
Volume27
DOIs
StatePublished - Sep 2022
Externally publishedYes

Keywords

  • Brachytherapy
  • Palladium-103
  • Plaque
  • Retinoblastoma
  • Survival
  • Visual acuity

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