Oxidative Cyclization-Induced Activation of a Phosphoinositide 3-Kinase Inhibitor for Enhanced Selectivity of Cancer Chemotherapeutics

Keyphrases

• Induced Activation 100%
• Phosphatidylinositol 3-kinase Inhibitor 100%
• Enhanced Selectivity 100%
• Cancer Chemotherapeutics 100%
• Oxidative Cyclization 100%
• Cancer Cells 33%
• Cell Behavior 33%
• Acute Myeloid Leukemia 33%
• Leukemia Cells 33%
• Co-treatment 33%
• Liver Microsomes 33%
• Antioxidant 33%
• Cytosine Arabinoside 33%
• Prodrug 33%
• Non-cancer 33%
• Doxorubicin 33%
• Cyclization 33%
• Anticancer Agents 33%
• Acute Myeloid Leukemia Cells 33%
• Reactive Oxygen Species 33%
• Synergistic Activity 33%
• Compounds Activity 33%
• Selective Anticancer Activity 33%
• Ether Cleavage 33%

Pharmacology, Toxicology and Pharmaceutical Science

• Malignant Neoplasm 100%
• Phosphatidylinositol 3 Kinase Inhibitor 100%
• Acute Myeloid Leukemia 66%
• Reactive Oxygen Metabolite 33%
• Cytarabine 33%
• Anticarcinogen 33%
• Doxorubicin 33%
• Oxidizing Agent 33%
• Antioxidant 33%
• Prodrug 33%