Overview of chronic health risks associated with phosphorus excess

Swati Mehta, Jaime Uribarri

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review


Although phosphorus is an essential nutrient, in excess it could be linked to tissue damage by a variety of mechanisms resulting from either direct precipitation with calcium or secondary to excess of hormonal factors involved in its endocrine regulation, specically the secretion and action of broblast growth factor 23 and parathyroid hormone. This excess phosphorus has been associated with disordered mineral metabolism, vascular calcications, cardiovascular disease, chronic kidney disease, and bone loss. This chapter explores many of chronic health risks that have been associated with excess phosphorus in patients with chronic kidney disease, as well as in healthy individuals.

Original languageEnglish
Title of host publicationDietary Phosphorus
Subtitle of host publicationHealth, Nutrition, and Regulatory Aspects
PublisherCRC Press
Number of pages9
ISBN (Electronic)9781498706971
ISBN (Print)9781498706964
StatePublished - 1 Jan 2017


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