Abstract

This is a comprehensive review and re-analysis of available literature to assess the outcome of lung cancer presenting as nonsolid nodules (NSNs), a more indolent form of cancer. PubMed and EMBASE were searched for articles reporting on CT-detected lung cancers manifesting as NSNs published in English on or before July 17, 2015. Only studies including clinicopathologic data, lung cancer-specific survival, or overall survival were included. Data extraction was performed by three independent reviewers using prespecified criteria. Twenty-four articles from 5 countries met criteria and they included 704 subjects with 712 lung cancers manifesting as NSNs. Each article reported from 2 to 100 lung cancer cases with a median follow up of 18-51 months. All NSNs were Stage I adenocarcinoma without pathologic nodal involvement upon resection, except for one case in which the NSN progressed to become part-solid nodule after 6 years of follow-up. The five-year lung cancer-specific survival rate was 100%. These findings suggest an indolent course for lung cancers manifesting as NSNs.

Original languageEnglish
Pages (from-to)35-42
Number of pages8
JournalLung Cancer
Volume97
DOIs
StatePublished - 1 Jul 2016

Keywords

  • Lung neoplasm
  • Screening
  • Surgery
  • Surveillance
  • Survival

Fingerprint

Dive into the research topics of 'Outcomes of lung cancers manifesting as nonsolid nodules'. Together they form a unique fingerprint.

Cite this