@article{1bd8b04933634426a92f2ec8a5420d7b,
title = "Outcomes of living liver donor candidate evaluations in the Living Donor Collective pilot registry",
abstract = "Background: To gather information on long-term outcomes after living donation, the Scientific Registry of Transplant Recipients (SRTR) conducted a pilot on the feasibility of establishing a comprehensive donor candidate registry. Methods: A convenience sample of 6 US living liver donor programs evaluated 398 consecutive donor candidates in 2018, ending with the March 12, 2020, COVID-19 emergency. Results: For 333/398 (83.7%), the donor or program decided whether to donate; 166/333 (49.8%) were approved, and 167/333 (50.2%) were not or opted out. Approval rates varied by program, from 27.0% to 63.3% (median, 46%; intraquartile range, 37.3–51.1%). Of those approved, 90.4% were white, 57.2% were women, 83.1% were < 50 years, and 85.5% had more than a high school education. Of 167 candidates, 131 (78.4%) were not approved or opted out because of: medical risk (10.7%); chronic liver disease risk (11.5%); psychosocial reasons (5.3%); candidate declined (6.1%); anatomical reasons increasing recipient risk (26.0%); recipient-related reasons (33.6%); finances (1.5%); or other (5.3%). Conclusions: A comprehensive national registry is feasible and necessary to better understand candidate selection and long-term outcomes. As a result, the US Health Resources and Services Administration asked SRTR to expand the pilot to include all US living donor programs.",
keywords = "decision making, liver failure, liver transplantation, risk assessment, scientific registry of transplant recipients",
author = "{the Living Donor Collective participants} and Kasiske, {Bertram L.} and Ahn, {Yoon Son} and Michael Conboy and Dew, {Mary Amanda} and Christian Folken and Levan, {Macey L.} and Abhi Humar and Israni, {Ajay K.} and Rudow, {Dianne La Pointe} and Trotter, {James F.} and Massie, {Allan B.} and Donald Musgrove",
note = "Funding Information: The US Government (and others acting on its behalf) retains a paid-up, nonexclusive, irrevocable, worldwide license for all works produced under the SRTR contract, and to reproduce them, prepare derivative works, distribute copies to the public, and perform publicly and display publicly, by or on behalf of the Government. The views expressed herein are those of the authors and not necessarily those of the US Government. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. The authors thank SRTR colleague Mary Van Beusekom, MS, ELS, for manuscript editing. The authors also thank the Living Donor Collective participants (listed alphabetically by institution): Departments of Medicine and Surgery, Baylor University Medical Center, Dallas, Texas: Sumeet K. Asrani, MD, MSc; Mohammad Amin Fallahzadeh, MD, MPH; Department of Surgery, Emory University School of Medicine, Atlanta, Georgia: Sharon B. Mathews; Tiffany DeArmas; Kenneth A. Newell, MD, PhD Division of Nephrology, Department of Medicine, Hennepin County Medical Center, Minneapolis, Minnesota: Eugenia Steffens, RN; Jeffrey H. Wang, MD Departments of Surgery and Epidemiology, Johns Hopkins University, Baltimore, Maryland: Dorry Segev, MD, PhD; Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN: Sandra J. Taler, MD; and Mayo Clinic William J. von Liebig Center for Transplantation and Clinical Regeneration, Rochester, Minnesota: Jacqulyn Reiter; Julie Gecox Hanson, CCPR; Department of Surgery, Division of Transplantation, University of Minnesota, Minneapolis, Minnesota: Arthur J. Matas, MD; and Solid Organ Transplant Abstraction and Registry, MHealth Fairview, University of Minnesota, Minneapolis, Minnesota; Cindy Charn; Vickie Bartels, Judy Witte, RN, BMT-SOT; Recanati/Miller Transplantation Institute, Mount Sinai Hospital, New York, New York: Brandy Haydel, CCRC; Megan Czurda, MPH; Departments of Psychiatry and Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania: Dana Jorgenson, PhD, MPH; Laurie Tubb; Erin McMahon; Saint Louis University Center for Abdominal Transplantation, St. Louis, Missouri: Krista L. Lentine, MD, PhD; Cody Wooley, RN; David Geffen School of Medicine at University of California at Los Angeles, Kidney Transplant Program, Los Angeles, California: A. D. Waterman, PhD; M. Dunbar-Forrest; Grace Kim; Gabe M. Danovitch, MD. Publisher Copyright: {\textcopyright} 2021 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.",
year = "2021",
month = sep,
doi = "10.1111/ctr.14394",
language = "English",
volume = "35",
journal = "Clinical Transplantation",
issn = "0902-0063",
publisher = "Wiley-Blackwell Publishing Ltd",
number = "9",
}