Osteoporosis: An unusual presentation of childhood Crohn's disease

M. Thearle; M. Horlick; J. P. Bilezikian; J. Levy; J. M. Gertner; L. S. Levine; M. Harbison; W. Berdon; S. E. Oberfield

doi:10.1210/jc.85.6.2122

Osteoporosis: An unusual presentation of childhood Crohn's disease

M. Thearle, M. Horlick, J. P. Bilezikian, J. Levy, J. M. Gertner, L. S. Levine, M. Harbison, W. Berdon, S. E. Oberfield

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Abstract

Osteoporosis is known to be associated with Crohn's disease. We report a 12-yr-old boy without a history of steroid use, in whom severe osteoporosis and multiple collapsed vertebrae were the presenting manifestations of Crohn's disease. After treatment of the Crohn's disease, he resumed normal growth and progressed through puberty. Concomitantly, he demonstrated a substantial recovery of vertebral bone mineral density and structure. Possible pathophysiological mechanisms underlying the osteoporosis and the subsequent improvement in bone density are discussed.

Original language	English
Pages (from-to)	2122-2126
Number of pages	5
Journal	Journal of Clinical Endocrinology and Metabolism
Volume	85
Issue number	6
DOIs	https://doi.org/10.1210/jc.85.6.2122
State	Published - 2000
Externally published	Yes

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abstract = "Osteoporosis is known to be associated with Crohn's disease. We report a 12-yr-old boy without a history of steroid use, in whom severe osteoporosis and multiple collapsed vertebrae were the presenting manifestations of Crohn's disease. After treatment of the Crohn's disease, he resumed normal growth and progressed through puberty. Concomitantly, he demonstrated a substantial recovery of vertebral bone mineral density and structure. Possible pathophysiological mechanisms underlying the osteoporosis and the subsequent improvement in bone density are discussed.",

author = "M. Thearle and M. Horlick and Bilezikian, {J. P.} and J. Levy and Gertner, {J. M.} and Levine, {L. S.} and M. Harbison and W. Berdon and Oberfield, {S. E.}",

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T2 - An unusual presentation of childhood Crohn's disease

AU - Thearle, M.

AU - Horlick, M.

AU - Bilezikian, J. P.

AU - Levy, J.

AU - Gertner, J. M.

AU - Levine, L. S.

AU - Harbison, M.

AU - Berdon, W.

AU - Oberfield, S. E.

PY - 2000

Y1 - 2000

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AB - Osteoporosis is known to be associated with Crohn's disease. We report a 12-yr-old boy without a history of steroid use, in whom severe osteoporosis and multiple collapsed vertebrae were the presenting manifestations of Crohn's disease. After treatment of the Crohn's disease, he resumed normal growth and progressed through puberty. Concomitantly, he demonstrated a substantial recovery of vertebral bone mineral density and structure. Possible pathophysiological mechanisms underlying the osteoporosis and the subsequent improvement in bone density are discussed.

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JO - Journal of Clinical Endocrinology and Metabolism

JF - Journal of Clinical Endocrinology and Metabolism

IS - 6

ER -

Osteoporosis: An unusual presentation of childhood Crohn's disease

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