Osteophyte induced lung fibrosis prevalence and osteophyte qualities predicting disease

Mary Salvatore; Claudia I. Henschke; Rowena Yip; Sukhdeep Kaur; Kunwei Li; Maria Padilla; David Yankelevitz

doi:10.1016/j.clinimag.2017.02.008

Osteophyte induced lung fibrosis prevalence and osteophyte qualities predicting disease

Mary Salvatore, Claudia I. Henschke, Rowena Yip, Sukhdeep Kaur, Kunwei Li, Maria Padilla, David Yankelevitz

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

Objective To determine the prevalence of osteophyte induced lung fibrosis (OIF) and its relationship to osteophyte size, location, and surrounding fat. Methods 94 CT scans of the chest were reviewed, size of the largest osteophyte and the presence of fibrosis were recorded. Results Presence of fibrosis was higher among patient with large (> 10 mm) osteophytes compared to those with small (1–10 mm) osteophytes. Age and presence of periosteophyte fat were significantly associated with presence of fibrosis. Conclusions As the size of an osteophyte increases, there is a greater likelihood of lung fibrosis. Subpleural fat protects the lung from OIF.

Original language	English
Pages (from-to)	1-4
Number of pages	4
Journal	Clinical Imaging
Volume	44
DOIs	https://doi.org/10.1016/j.clinimag.2017.02.008
State	Published - 1 Jul 2017

Keywords

Osteophyte
Pulmonary fibrosis
UIP
Usual interstitial pneumonitis

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10.1016/j.clinimag.2017.02.008

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title = "Osteophyte induced lung fibrosis prevalence and osteophyte qualities predicting disease",

abstract = "Objective To determine the prevalence of osteophyte induced lung fibrosis (OIF) and its relationship to osteophyte size, location, and surrounding fat. Methods 94 CT scans of the chest were reviewed, size of the largest osteophyte and the presence of fibrosis were recorded. Results Presence of fibrosis was higher among patient with large (> 10 mm) osteophytes compared to those with small (1–10 mm) osteophytes. Age and presence of periosteophyte fat were significantly associated with presence of fibrosis. Conclusions As the size of an osteophyte increases, there is a greater likelihood of lung fibrosis. Subpleural fat protects the lung from OIF.",

keywords = "Osteophyte, Pulmonary fibrosis, UIP, Usual interstitial pneumonitis",

author = "Mary Salvatore and Henschke, {Claudia I.} and Rowena Yip and Sukhdeep Kaur and Kunwei Li and Maria Padilla and David Yankelevitz",

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doi = "10.1016/j.clinimag.2017.02.008",

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T1 - Osteophyte induced lung fibrosis prevalence and osteophyte qualities predicting disease

AU - Salvatore, Mary

AU - Henschke, Claudia I.

AU - Yip, Rowena

AU - Kaur, Sukhdeep

AU - Li, Kunwei

AU - Padilla, Maria

AU - Yankelevitz, David

PY - 2017/7/1

Y1 - 2017/7/1

N2 - Objective To determine the prevalence of osteophyte induced lung fibrosis (OIF) and its relationship to osteophyte size, location, and surrounding fat. Methods 94 CT scans of the chest were reviewed, size of the largest osteophyte and the presence of fibrosis were recorded. Results Presence of fibrosis was higher among patient with large (> 10 mm) osteophytes compared to those with small (1–10 mm) osteophytes. Age and presence of periosteophyte fat were significantly associated with presence of fibrosis. Conclusions As the size of an osteophyte increases, there is a greater likelihood of lung fibrosis. Subpleural fat protects the lung from OIF.

AB - Objective To determine the prevalence of osteophyte induced lung fibrosis (OIF) and its relationship to osteophyte size, location, and surrounding fat. Methods 94 CT scans of the chest were reviewed, size of the largest osteophyte and the presence of fibrosis were recorded. Results Presence of fibrosis was higher among patient with large (> 10 mm) osteophytes compared to those with small (1–10 mm) osteophytes. Age and presence of periosteophyte fat were significantly associated with presence of fibrosis. Conclusions As the size of an osteophyte increases, there is a greater likelihood of lung fibrosis. Subpleural fat protects the lung from OIF.

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KW - Pulmonary fibrosis

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Osteophyte induced lung fibrosis prevalence and osteophyte qualities predicting disease

Abstract

Keywords

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