Osteochondrodystrophy (ocd): A new autosomal recessive mutation in the mouse

H. O. Sweet, R. T. Bronson

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

Osteochondrodystrophy (ocd) is a new autosomal recessive mouse mutation characterized by a short, slightly domed head, reduced body size, disproportionately shortened long bones of the legs, supination of the forefeet, and short thickened tail. Histologically, the epiphyses are thinner than normal. The columnar organization of the proliferative zone of cartilage is disorderly, with pleomorphic and occasionally necrotic chondrocytes. Osteochondrodystrophy has been mapped to a position near the centromere of mouse chromosome (Chr) 19.

Original languageEnglish
Pages (from-to)140-144
Number of pages5
JournalJournal of Heredity
Volume82
Issue number2
DOIs
StatePublished - Mar 1991
Externally publishedYes

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