Osseous metaplasia in benign colorectal polyps

G. M. Groisman, K. J. Benkov, V. Adsay, M. R. Dische

Research output: Contribution to journalArticlepeer-review

30 Scopus citations


We report two unique cases of metaplastic ossification occurring within a tubulovillous adenoma and a juvenile polyp. In both lesions, well-formed bony spicules were present that were adjacent to living epithelial cells. The metaplastic bone revealed vimentin positivity and cytokeratin negativity. The pathogenesis of osseous metaplasia in colorectal tumors remains unclear, but the process seems to have no clinical significance.

Original languageEnglish
Pages (from-to)64-65
Number of pages2
JournalArchives of Pathology and Laboratory Medicine
Issue number1
StatePublished - 1994


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