Organophosphorus derivatives containing piperazine dithiosemicarbazones as chemotherapeutants against fungal pathogens of sugarcane

Ruchi Chandra, O. P. Pandey, S. K. Sengupta

Research output: Contribution to journalArticlepeer-review

20 Scopus citations

Abstract

Five novel organophosphorus derivatives have been synthesized by the reactions of O,O-diethylchlorophosphate with piperazine dithiosemicarbazones. The derivatives have been characterized on the basis of analyses and spectral (IR, 1H NMR) data. Fungicidal activities of these derivatives against Colletotrichum falcatum, Fusarium oxysporum, and Curvularia pallescence have been evaluated. The screening results have been correlated with the structural features of the tested compounds. Organophosphorus derivatives containing 1,4-bis(4-chlorobenzaldehyde)piperazine dithiosemicarbazone and 1,4-bis(4-methoxybenzaldehyde)piperazine dithiosemicarbazone proved to be more active than some prevalent commercial synthetic fungicides.

Original languageEnglish
Pages (from-to)2181-2184
Number of pages4
JournalJournal of Agricultural and Food Chemistry
Volume53
Issue number6
DOIs
StatePublished - 23 Mar 2005
Externally publishedYes

Keywords

  • Fungal pathogens
  • IR
  • NMR
  • Organophosphorus derivatives
  • Sugarcane
  • Synthesis

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