Oral nimodipine inhibits the ovarian cycle in mice

Ofer Fainaru, Ross Firestone, Robert F. Casper

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Nimodipine, a calcium-channel blocker that can cross the blood-brain barrier, has been shown to inhibit pulsatile GnRH release in vitro. We now show that oral nimodipine can effectively inhibit the ovarian cycle in mice in a dose-related manner.

Original languageEnglish
Pages (from-to)1494-1496
Number of pages3
JournalFertility and Sterility
Volume95
Issue number4
DOIs
StatePublished - 15 Mar 2011
Externally publishedYes

Keywords

  • Nimodopine
  • calcium blocker
  • estrus cycle

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