Oral immunotherapy for food allergy

The IgE-mediated food allergy associated with risk for fatal anaphylaxis has been the subject of multiple immunotherapy studies in the past decade. The growing body of evidence suggests that for IgE-mediated food allergy immunomodulation through food immunotherapy is possible; however, the extent of protection provided by such treatment is highly variable. The capacity for food immunotherapy to restore permanent oral tolerance to food has not been demonstrated conclusively. In this review we discuss the most relevant studies of food oral immunotherapy.