Optimization of 4-Aminopiperidines as Inhibitors of Influenza A Viral Entry That Are Synergistic with Oseltamivir

Keyphrases

• Influenza A 100%
• Hemagglutinin 100%
• Influenza-like Illness 100%
• Viral Entry 100%
• H5N1 100%
• Oseltamivir 100%
• 4-Aminopiperidine 100%
• Virus 50%
• Viral 50%
• Mechanism of Action 50%
• New Therapeutics 50%
• Therapeutic Potential 50%
• Vaccination 50%
• Binding Site 50%
• Influenza Virus 50%
• Vietnam 50%
• Acute Treatment 50%
• Resistant Strains 50%
• Circulating Strains 50%
• Orally Bioavailable 50%
• Synergistic Activity 50%
• Docking Studies 50%
• Fast-acting 50%
• Puerto Rico 50%
• Acylate 50%
• Entry Inhibitor 50%
• Effective Mechanism 50%
• Viral Titer 50%
• Seasonal Influenza 50%
• Influenza A (H1N1) Virus 50%
• Co-epidemics 50%
• Oseltamivir-resistant 50%
• Addition Compounds 50%
• H274Y mutation 50%

Pharmacology, Toxicology and Pharmaceutical Science

• Influenza A 100%
• Oseltamivir 100%
• Influenza 66%
• Influenza A Virus (H5N1) 66%
• Binding Site 33%
• Influenzavirus A 33%
• Influenza A Virus (H1N1) 33%
• Pandemic 33%
• Seasonal Influenza 33%
• Hemagglutinin 33%
• Fusion Inhibitor 33%
• Virus Hemagglutinin 33%

Immunology and Microbiology

• Viral Entry 100%
• Influenza 100%
• Influenza A Virus (H5N1) 66%
• Viral Load 33%
• Binding Site 33%
• Hemagglutinin 33%
• Virus Hemagglutinin 33%
• Influenza A Virus (H1N1) 33%
• Influenzavirus A 33%