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Opsonic activity of guinea pig serum is reduced by in vivo administration of carcinogenic nitrosamines

  • Z. Marom
  • , V. Brade
  • , H. R. Colten

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

The administration of each of four carcinogenic nitrosamines to normal guinea pigs resulted in decreased opsonic activity of their sera but did not affect the capacity of their peritoneal macrophages to phagocytize particles opsonized with normal serum. Diphenylnitrosamine, a noncarcinogenic analogue, had no significant effect on opsonic or phagocytic activity.

Original languageEnglish
Pages (from-to)983-985
Number of pages3
JournalJournal of Immunology
Volume120
Issue number3
StatePublished - 1978
Externally publishedYes

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