Opposed-phase MRI for fat quantification in fat-water phantoms with 1H MR spectroscopy to resolve ambiguity of fat or water dominance

Jerry S. Chang, Bachir Taouli, Nouha Salibi, Elizabeth M. Hecht, Deanna G. Chin, Vivian S. Lee

Research output: Contribution to journalArticlepeer-review

34 Scopus citations

Abstract

OBJECTIVE. The purpose of the study was to quantify the fat fraction in nine fat-water phantoms containing 0-80% fat using opposed-phase imaging with the qualitative guidance of 1H MR spectroscopy (MRS), which was used by observer 1 to visually assess the sizes of the water and fat peaks to apply two alternative mathematic formulas for the calculation of the fat fraction. In addition, the fat fraction was also quantified directly with 1H MRS as an independent method by two observers (observers 2 and 3). CONCLUSION. The fat fraction calculated with opposed-phase imaging (FFOPI) and that calculated with 1H MRS (FFMRS) correlated well with the known fat fractions of the phantoms (FFP): r = 0.99 for FF OPI; p < 0.0001 and r = 0.96-0.98 for FFMRS; p < 0.001, for observers 2 and 3, respectively. Opposed-phase imaging should be combined with 1H MRS to ensure accurate quantification of the fat fraction.

Original languageEnglish
Pages (from-to)249
Number of pages1
JournalAmerican Journal of Roentgenology
Volume187
Issue number1
DOIs
StatePublished - Jul 2006
Externally publishedYes

Keywords

  • Liver disease
  • MRI
  • SPECT

Fingerprint

Dive into the research topics of 'Opposed-phase MRI for fat quantification in fat-water phantoms with 1H MR spectroscopy to resolve ambiguity of fat or water dominance'. Together they form a unique fingerprint.

Cite this