TY - JOUR
T1 - Opioid Overdose and Serotonin Syndrome due to Gastric Bezoar in a Woman with Autism and Pica Behaviour
AU - Palimaru, Iolanda
AU - Guetta, Michaël
AU - Cravero, Cora
AU - Fron, Clémence
AU - Cohen, David
AU - Giannitelli, Marianna
N1 - Publisher Copyright:
© 2021 Iolanda Palimaru et al.
PY - 2021
Y1 - 2021
N2 - We are presenting the case of a 38-year-old woman with nonverbal autism and intellectual disability, hospitalized in a neurobehavioural unit because of a pica behaviour for 3 years. During the hospitalization, the patient presented an episode of pain, agitation, restlessness, rhabdomyolysis, coma, tachycardia, hyperthermia, shivering, and diarrhoea. The main hypothesis raised was tramadol overdose because of the immediate antidote response to the injection of naloxone 0,4 mg/mL. Even if we did not exceed the recommended prescription dosage of tramadol, the presence of gastric bezoar slowed the absorption of the drug, and the consequence was an opioid overdose and serotonin syndrome.
AB - We are presenting the case of a 38-year-old woman with nonverbal autism and intellectual disability, hospitalized in a neurobehavioural unit because of a pica behaviour for 3 years. During the hospitalization, the patient presented an episode of pain, agitation, restlessness, rhabdomyolysis, coma, tachycardia, hyperthermia, shivering, and diarrhoea. The main hypothesis raised was tramadol overdose because of the immediate antidote response to the injection of naloxone 0,4 mg/mL. Even if we did not exceed the recommended prescription dosage of tramadol, the presence of gastric bezoar slowed the absorption of the drug, and the consequence was an opioid overdose and serotonin syndrome.
UR - http://www.scopus.com/inward/record.url?scp=85122521678&partnerID=8YFLogxK
U2 - 10.1155/2021/7334467
DO - 10.1155/2021/7334467
M3 - Article
AN - SCOPUS:85122521678
SN - 2090-682X
VL - 2021
JO - Case Reports in Psychiatry
JF - Case Reports in Psychiatry
M1 - 7334467
ER -