Ophthalmoplegic migraine: Amelioration by flufenamic acid, a prostaglandin inhibitor

J. M. Rabey, Y. Vardi, D. Van Dyck, M. Streifler

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

It was recently suggested that prostaglandin release (especially PGE1 and PGF(2α)) plays a key role in the development of the migrainous attack. Based on this hypothesis a therapeutic trial with flufenamic acid (a prostaglandin inhibitor of the fenamates group) was conducted during 1 yr in 5 patients suffering from recurrent ophthalmoplegic migraine. We treated 25 migrainous attacks; in 22 of them the patients reported marked alleviation of the headaches and only in 2 occasions a partial third nerve palsy accompanied the attack.

Original languageEnglish
Pages (from-to)148-152
Number of pages5
JournalOphthalmologica
Volume175
Issue number3
DOIs
StatePublished - 1977
Externally publishedYes

Fingerprint

Dive into the research topics of 'Ophthalmoplegic migraine: Amelioration by flufenamic acid, a prostaglandin inhibitor'. Together they form a unique fingerprint.

Cite this