Okadaic acid: a new probe for the study of cellular regulation

Philip Cohen; Charles F.B. Holmes; Yasumasa Tsukitani

doi:10.1016/0968-0004(90)90192-E

Okadaic acid: a new probe for the study of cellular regulation

Philip Cohen
, Charles F.B. Holmes
, Yasumasa Tsukitani

Research output: Contribution to journal › Review article › peer-review

1416 Scopus citations

Abstract

The tumour promoter okadaic acid is a potent and specific inhibitor of protein phosphatases 1 and 2A. Here we review recent studies which demonstrate that this toxin is extremely useful for identifying biological processes that are controlled through the reversible phosphorylation of proteins.

Original language	English
Pages (from-to)	98-102
Number of pages	5
Journal	Trends in Biochemical Sciences
Volume	15
Issue number	3
DOIs	https://doi.org/10.1016/0968-0004(90)90192-E
State	Published - Mar 1990
Externally published	Yes

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title = "Okadaic acid: a new probe for the study of cellular regulation",

abstract = "The tumour promoter okadaic acid is a potent and specific inhibitor of protein phosphatases 1 and 2A. Here we review recent studies which demonstrate that this toxin is extremely useful for identifying biological processes that are controlled through the reversible phosphorylation of proteins.",

author = "Philip Cohen and Holmes, \{Charles F.B.\} and Yasumasa Tsukitani",

year = "1990",

month = mar,

doi = "10.1016/0968-0004(90)90192-E",

language = "English",

volume = "15",

pages = "98--102",

journal = "Trends in Biochemical Sciences",

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T1 - Okadaic acid

T2 - a new probe for the study of cellular regulation

AU - Cohen, Philip

AU - Holmes, Charles F.B.

AU - Tsukitani, Yasumasa

PY - 1990/3

Y1 - 1990/3

N2 - The tumour promoter okadaic acid is a potent and specific inhibitor of protein phosphatases 1 and 2A. Here we review recent studies which demonstrate that this toxin is extremely useful for identifying biological processes that are controlled through the reversible phosphorylation of proteins.

AB - The tumour promoter okadaic acid is a potent and specific inhibitor of protein phosphatases 1 and 2A. Here we review recent studies which demonstrate that this toxin is extremely useful for identifying biological processes that are controlled through the reversible phosphorylation of proteins.

UR - https://www.scopus.com/pages/publications/0025181418

U2 - 10.1016/0968-0004(90)90192-E

DO - 10.1016/0968-0004(90)90192-E

M3 - Review article

C2 - 2158158

AN - SCOPUS:0025181418

SN - 0968-0004

VL - 15

SP - 98

EP - 102

JO - Trends in Biochemical Sciences

JF - Trends in Biochemical Sciences

IS - 3

ER -

Okadaic acid: a new probe for the study of cellular regulation

Abstract

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